Researchers Identify ‘Bridge’ State Necessary for Cellular Reprogramming
Researchers showed that mature cells enter a unique transition state when being reprogrammed to iPS cells. Deconstructing the reprogramming process helped researchers better understand pluripotency. [Press release from Stanford Medicine discussing online prepublication in Nature] Press Release|Abstract
Reprogramming of Cell Fate: Epigenetic Memory and the Erasure of Memories Past
The authors explore the potential roles and mechanisms by which histone variants, chromatin remodeling enzymes, and histone and DNA modifications contribute to the stability of cell identity and/or provide a permissive environment for cell fate change during cellular reprogramming. [EMBO J] Full Article
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INDUSTRY NEWS
£25.7 Million to Create Research Powerhouse
A £25.7 million funding boost will advance biological research and aid the quest for new therapies to treat damaged tissues. The investment by the UK Government will enable the University of Edinburgh to create a new biology complex with world-leading laboratory space for 350 researchers and to establish a new Centre for Tissue Repair. [The University of Edinburgh] Press Release
$10 Million Gift Establishes Center to Develop Personalized Medicine to Fight Cancer
A $10 million gift from entrepreneurs Emmet and Toni Stephenson and their daughter Tessa Stephenson Brand will further the pioneering efforts of Keck Medicine of the University of Southern California (USC) Professor David B. Agus, MD, to change the way cancer is viewed and treated and forge a path to personalized medicine. [Keck Medicine of USC] Press Release
Cold Spring Harbor Laboratory, Hospital Join Forces to Develop Cancer Drugs
The famed Cold Spring Harbor Laboratory is making a major foray into more applied drug development. The lab and North Shore-LIJ Health System, a local hospital system, announced a new alliance and a more than $120 million investment aimed at moving basic cancer discoveries into the clinic. [ScienceInsider] Editorial
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