Fine-Tuning Next-Generation Genome Editing Tools|
The authors compare available methods for detecting, measuring, and analyzing off-target mutations. They particularly focus on CRISPR/Cas9 regarding various methods, tweaks, and software tools available to nullify off-target effects. [Trends Biotechnol] Abstract
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Global Standards for Stem-Cell Research|
In response to scientific progress and evolving ethical concerns, the International Society for Stem Cell Research issued updated and extended guidelines for work involving the manipulation of stem cells and the translation of that work into medical therapies. [Nature News] Editorial
‘Brexit’ Would Hit U.K. Research Hard, Report Says
Leaving the European Union would cause a steep drop in research funding for scientists in the United Kingdom, according to a new study—and it’s unclear whether the country can “buy its way back” into European funding schemes under favorable conditions. [ScienceInsider] Editorial